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Introducing XELSTRYM: ADHD treatment that lets you control

Your time,
Your way
The first and only amphetamine patch

Work with your healthcare provider to determine when to apply and when to remove XELSTRYM to help fit ADHD treatment into your changing schedule.

XELSTRYM should be removed within 9 hours.

Your ADHD treatment should be flexible to meet the demands of your daily schedule

No matter where you are in your day—working, exercising, socializing with friends or family, or just taking some “me” time—symptom management should align with your daily routine. It is important to work with your healthcare provider for flexibility with your schedule.

Starting your day
Presenting at work
“Me” time

What is XELSTRYM?

The first and only amphetamine treatment for ADHD that uses patch technology to passively deliver medication through the skin.

XELSTRYM has the same active metabolite (dextroamphetamine) as Vyvanse®*, a medication used to treat ADHD since 2007.

This technology allows you and your healthcare provider to tailor your ADHD treatment to meet your daily schedule. Work with your healthcare provider to determine when to apply and when to remove XELSTRYM.

XELSTRYM should be removed within 9 hours.

There are no head-to-head safety or efficacy studies comparing Vyvanse® and XELSTRYM.
*VYVANSE® is a registered trademark of Takeda Pharmaceuticals U.S.A., Inc.

Download the XELSTRYM Patient Brochure to learn more

Download PDF

XELSTRYM is a clear and discreet patch that can be worn under your clothing

Four dosage strengths provide flexible options

Work with your healthcare provider to tailor your dose to meet your needs

Patches, US nickel, and golf ball not shown at actual size.

  • Use one patch daily (per 24 hours)
  • Do not wear the patch for more than 9 hours
  • Select a different application site when a new patch is applied
  • See full Instructions for Use

XELSTRYM can be worn during most of your daily activities

Here are the things you can do while wearing XELSTRYM
YESAVOID
Showering*
Bathing*
Swimming*
Activities that cause sweating†
Direct heat‡

*Patients should check to see if the patch has become loose after bathing, showering, or swimming.

†Patients should check their patch fit if they sweat excessively.

‡After applying XELSTRYM, patients should avoid exposing the application site to direct external heat sources, such as hair dryers, heating pads or electric blankets, heat lamps, saunas, hot tubs, and heated water beds. Exposure to heat can cause too much medicine to pass into their body and cause serious side effects.

How do I apply the patch?

Watch this video to learn how to use XELSTRYM.

Download the Instructions for Use brochure to learn more about how to use XELSTRYM

Download PDF

What are the most common side effects of XELSTRYM in adults?

Decreased appetite Increased blood pressure
Headache Muscle twitching (tics)
Trouble sleeping Vomiting
Stomach pain Irritability
Nausea Increased heart rate

Application site reactions have happened while wearing XELSTRYM and after removal of the patch. Symptoms include pain, itching, burning feeling, redness, discomfort, or swelling at the application site. Call your healthcare provider if you or your child develop any application site reactions that do not resolve on their own.

XELSTRYM offers a program to help you right from the start through the Noven Care Access Network (Noven C.A.N.™)

Network Pharmacy Savings Offer
  • FREE 1st Fill for All Eligible Patients
  • Fills 2-12
    • Insured, Covered Patients Pay as Little as $0
    • Insured, Not Covered Patients Pay as Little as $25
Register for Co-Pay Assistance

If you choose to fill at a pharmacy that is outside of the Noven C.A.N.™ Pharmacy Partnership, we still have you covered. Eligible patients will still pay $0 for their first fill and as little as $50 for additional fills.

Click here for full terms and conditions.

Noven C.A.N.™ is available to provide assistance and access for you every step of the way

Noven Care Access NetworkCall 833-483-2178
Monday-Friday, 8:00 AM - 6:30 PM CST

Pharmacy Locator ServiceCall 800-420-2719

Resources & Support

These tools and resources will help you learn more about XELSTRYM and how to find additional support for ADHD
Instructions for Use BrochurePatient
BrochureProper Use of Stimulant Medications

Professional organizations that can help you manage ADHD

Attention Deficit Disorder Organization (ADDA) Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD) National Institute of Mental Health (NIMH)
Important Safety Information
What is XELSTRYM?

XELSTRYM is a central nervous system stimulant prescription medicine used for the treatment of Attention-Deficit Hyperactivity Disorder (ADHD) in adults and children 6 years and older. It is not known if XELSTRYM is safe and effective in children younger than 6 years of age.

IMPORTANT SAFETY INFORMATION

Abuse and dependence: XELSTRYM, other amphetamine-containing medicines, and methylphenidate have a high chance for abuse and can cause physical and psychological dependence. Your healthcare provider (HCP) should check you or your child for signs of abuse and dependence before and during treatment with XELSTRYM.

  • Tell your HCP if you or your child has ever abused or been dependent on alcohol, prescription medicines or street drugs.
  • Your HCP can tell you how physical and psychological dependence and drug addiction are different.

XELSTRYM is a federally controlled substance (CII) because it contains amphetamine that can be a target for people who abuse prescription medicines or street drugs. Keep XELSTRYM in a safe place to protect it from theft. Never sell or give your XELSTRYM to anyone else because it may cause death or harm to them and it is against the law.

Do not use XELSTRYM if you or your child are:
  • Allergic to amphetamine or any of the ingredients in XELSTRYM. See the end of the Medication Guide for a complete list of ingredients in XELSTRYM.
  • Taking or have taken within the past 14 days a medicine called a monoamine oxidase inhibitor (MAOI), including the antibiotic linezolid or the intravenous medicine called methylene blue.
XELSTRYM can cause serious side effects, including:
  • Heart-related problems, including:
    • sudden death, stroke, and heart attack in adults
    • sudden death in children who have heart problems or heart defects
    • increased blood pressure and heart rate
    Your HCP should check you or your child carefully for heart problems before starting treatment with XELSTRYM. Tell your HCP if you or your child have any heart problems, heart defects, high blood pressure, or a family history of these problems. Your HCP should check your or your child’s blood pressure and heart rate regularly during treatment with XELSTRYM. Call your HCP or go to the nearest hospital emergency room right away if you or your child have any signs of heart problems such as chest pain, shortness of breath, or fainting during treatment with XELSTRYM.
  • Mental (psychiatric) problems, including: new or worse behavior and thought problems, new or worse bipolar illness, new psychotic symptoms (such as hearing voices, or seeing or believing things that are not real) or new manic symptoms. Tell your HCP about any mental problems you or your child have or about a family history of suicide, bipolar illness, or depression. Call your HCP right away if you or your child have any new or worsening mental symptoms or problems during treatment with XELSTRYM, especially hearing, seeing or believing things that are not real, or new manic symptoms.
  • Slowing of growth (height or weight) in children. Children should have their height and weight checked often while on XELSTRYM. Your HCP may stop treatment with XELSTRYM if your child is not growing or gaining height or weight as expected.
  • Circulation problems in fingers and toes (peripheral vasculopathy, including Raynaud’s phenomenon): fingers or toes may feel numb, cool, painful, fingers or toes may change color from pale, to blue, to red. Tell your HCP if you or your child has any numbness, pain, skin color change, or sensitivity to temperature in your fingers or toes. Call your HCP right away if you or your child have any signs of unexplained wounds appearing on fingers or toes while using XELSTRYM.
  • Serotonin syndrome: symptoms such as agitation, fast heartbeat, flushing, seizures, coma, sweating, loss of coordination, confusion, dizziness, tremors, stiff muscles, muscle twitching, seeing or hearing things that are not real (hallucinations), changes in blood pressure, high body temperature (hyperthermia), nausea, vomiting, or diarrhea may occur. Stop using XELSTRYM and call your HCP or go to the emergency room if symptoms occur. Serotonin syndrome may occur if XELSTRYM is taken with certain medicines and may be life-threatening.
  • Allergic skin rash (contact sensitization): Stop using XELSTRYM and tell your HCP right away if you or your child develop swelling or blisters at or around the application site.
  • Application site reactions have happened while wearing XELSTRYM and after removal of the patch. Symptoms include pain, itching, burning feeling, redness, discomfort, or swelling at the application site. Call your HCP if you or child develop any application site reactions that do not resolve on their own.
Before taking XELSTRYM tell your healthcare provider if you:
  • Are pregnant or plan to become pregnant. It is not known if XELSTRYM may harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. XELSTRYM can pass into your milk. Do not breastfeed while taking XELSTRYM. Talk to your doctor about the best way to feed your baby if you take XELSTRYM.
What should I avoid while using XELSTRYM?
  • Do not drive, operate heavy machinery, or do other potentially dangerous activities until you know how XELSTRYM affects you.
  • Avoid exposing the application site to direct external heat sources such as hair dryers, heating pads, electric blankets, heat lamps, saunas, hot tubs, and heated water beds as exposure to heat can cause too much medicine to pass into your body and cause serious side effects.
What are the possible side effects of XELSTRYM?
  • The most common side effects of XELSTRYM include:
    • decreased appetite
    • headache
    • trouble sleeping
    • stomach pain
    • nausea
    • increased blood pressure
    • muscle twitching (tics)
    • vomiting
    • irritability
    • increased heart rate

Please click here for the Medication Guide and Full Prescribing Information, including the BOXED WARNING.

To report suspected Adverse Reactions, contact Noven at 800-455-8070 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

There is a pregnancy registry for women who are exposed to XELSTRYM during pregnancy. The purpose of the registry is to collect information about the health of women exposed to XELSTRYM and their baby. If you or your child becomes pregnant during treatment with XELSTRYM, talk to your HCP about registering with the National Pregnancy Registry for Psychiatric Medications at 1-866-961-2388 or visit online at https://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/othermedications/

Important Safety Information
What is XELSTRYM?

XELSTRYM is a central nervous system stimulant prescription medicine used for the treatment of Attention-Deficit Hyperactivity Disorder (ADHD) in adults and children 6 years and older. It is not known if XELSTRYM is safe and effective in children younger than 6 years of age.

IMPORTANT SAFETY INFORMATION

Abuse and dependence: XELSTRYM, other amphetamine-containing medicines, and methylphenidate have a high chance for abuse and can cause physical and psychological dependence. Your healthcare provider (HCP) should check you or your child for signs of abuse and dependence before and during treatment with XELSTRYM.

  • Tell your HCP if you or your child has ever abused or been dependent on alcohol, prescription medicines or street drugs.
  • Your HCP can tell you how physical and psychological dependence and drug addiction are different.

XELSTRYM is a federally controlled substance (CII) because it contains amphetamine that can be a target for people who abuse prescription medicines or street drugs. Keep XELSTRYM in a safe place to protect it from theft. Never sell or give your XELSTRYM to anyone else because it may cause death or harm to them and it is against the law.

Do not use XELSTRYM if you or your child are:
  • Allergic to amphetamine or any of the ingredients in XELSTRYM. See the end of the Medication Guide for a complete list of ingredients in XELSTRYM.
  • Taking or have taken within the past 14 days a medicine called a monoamine oxidase inhibitor (MAOI), including the antibiotic linezolid or the intravenous medicine called methylene blue.
XELSTRYM can cause serious side effects, including:
  • Heart-related problems, including:
    • sudden death, stroke, and heart attack in adults
    • sudden death in children who have heart problems or heart defects
    • increased blood pressure and heart rate
    Your HCP should check you or your child carefully for heart problems before starting treatment with XELSTRYM. Tell your HCP if you or your child have any heart problems, heart defects, high blood pressure, or a family history of these problems. Your HCP should check your or your child’s blood pressure and heart rate regularly during treatment with XELSTRYM. Call your HCP or go to the nearest hospital emergency room right away if you or your child have any signs of heart problems such as chest pain, shortness of breath, or fainting during treatment with XELSTRYM.
  • Mental (psychiatric) problems, including: new or worse behavior and thought problems, new or worse bipolar illness, new psychotic symptoms (such as hearing voices, or seeing or believing things that are not real) or new manic symptoms. Tell your HCP about any mental problems you or your child have or about a family history of suicide, bipolar illness, or depression. Call your HCP right away if you or your child have any new or worsening mental symptoms or problems during treatment with XELSTRYM, especially hearing, seeing or believing things that are not real, or new manic symptoms.
  • Slowing of growth (height or weight) in children. Children should have their height and weight checked often while on XELSTRYM. Your HCP may stop treatment with XELSTRYM if your child is not growing or gaining height or weight as expected.
  • Circulation problems in fingers and toes (peripheral vasculopathy, including Raynaud’s phenomenon): fingers or toes may feel numb, cool, painful, fingers or toes may change color from pale, to blue, to red. Tell your HCP if you or your child has any numbness, pain, skin color change, or sensitivity to temperature in your fingers or toes. Call your HCP right away if you or your child have any signs of unexplained wounds appearing on fingers or toes while using XELSTRYM.
  • Serotonin syndrome: symptoms such as agitation, fast heartbeat, flushing, seizures, coma, sweating, loss of coordination, confusion, dizziness, tremors, stiff muscles, muscle twitching, seeing or hearing things that are not real (hallucinations), changes in blood pressure, high body temperature (hyperthermia), nausea, vomiting, or diarrhea may occur. Stop using XELSTRYM and call your HCP or go to the emergency room if symptoms occur. Serotonin syndrome may occur if XELSTRYM is taken with certain medicines and may be life-threatening.
  • Allergic skin rash (contact sensitization): Stop using XELSTRYM and tell your HCP right away if you or your child develop swelling or blisters at or around the application site.
  • Application site reactions have happened while wearing XELSTRYM and after removal of the patch. Symptoms include pain, itching, burning feeling, redness, discomfort, or swelling at the application site. Call your HCP if you or child develop any application site reactions that do not resolve on their own.
Before taking XELSTRYM tell your healthcare provider if you:
  • Are pregnant or plan to become pregnant. It is not known if XELSTRYM may harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. XELSTRYM can pass into your milk. Do not breastfeed while taking XELSTRYM. Talk to your doctor about the best way to feed your baby if you take XELSTRYM.
What should I avoid while using XELSTRYM?
  • Do not drive, operate heavy machinery, or do other potentially dangerous activities until you know how XELSTRYM affects you.
  • Avoid exposing the application site to direct external heat sources such as hair dryers, heating pads, electric blankets, heat lamps, saunas, hot tubs, and heated water beds as exposure to heat can cause too much medicine to pass into your body and cause serious side effects.
What are the possible side effects of XELSTRYM?
  • The most common side effects of XELSTRYM include:
    • decreased appetite
    • headache
    • trouble sleeping
    • stomach pain
    • nausea
    • increased blood pressure
    • muscle twitching (tics)
    • vomiting
    • irritability
    • increased heart rate

Please click here for the Medication Guide and Full Prescribing Information, including the BOXED WARNING.

To report suspected Adverse Reactions, contact Noven at 800-455-8070 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

There is a pregnancy registry for women who are exposed to XELSTRYM during pregnancy. The purpose of the registry is to collect information about the health of women exposed to XELSTRYM and their baby. If you or your child becomes pregnant during treatment with XELSTRYM, talk to your HCP about registering with the National Pregnancy Registry for Psychiatric Medications at 1-866-961-2388 or visit online at https://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/othermedications/